Custom Enzymes and Inhibitors
Thermo Scientific™ Modification Reagent
Deanimate unmethylated cytosines and convert them to uracils. Thermo Scientific™ EpiJET™ Modification Reagent is a component of the EpiJET™ Bisulfate Conversion Kit (K1461) and may be purchased separately when additional supply is needed for more reactions. Supplied in 5 x 0.7g aliquots.
Novus Biologicals™ Necrostatin-1 Inhibitor
ATP-competitive, allosteric inhibitor of receptor-interacting protein kinase 1 (RIPK1) (EC50 = 182nM)
Thermo Scientific™ Wash Buffer for Bisulfite Conversion Kit (concentrated)
Wash bound DNA to remove any contaminants from the modified DNA. Thermo Scientific™ EpiJET™ Wash Buffer (concentrated) is a component of the EpiJET™ Bisulfate Conversion Kit (K1461) and may be purchased separately when additional supply is needed. Provided in 9mL aliquots.
R&D Systems™ BostonBiochem UbiCREST Enzyme Set
Extensive quality control produces lot-to-lot consistency that instills confidence in results and ensures reproducibility.
R&D Systems™ clasto-Lactacystin beta Lactone
Potent, highly specific, irreversible and cell-permeable inhibitor that covalently modifies the beta subunits of the proteasome
Z-Val-Glu(OMe)-Ile-Asp(OMe)-Fluoromethylketone, MP Biomedicals™
Irreversibly inhibits activity of VEID-dependent caspases (e.g., caspase-6). Z-Val-Glu(OMe)-Ile-Asp(OMe)-Fluoromethylketone, MP Biomedicals is a synthetic peptide designed as a methyl ester to facilitate cell permeability. It is used for both in vitro and
BD Caspase-3 Inhibitor, Z-DEVD-FMK
Irreversible and cell permeable inhibitor of caspase-3
BD Caspase-8 Inhibitor, Z-IETD-FMKK
Irreversible and cell permeable inhibitor of caspase-8
BD Ac-DEVD-CHO Inhibitor
To identify and quantify Caspase-3 activity in apoptotic cells, and to study events downstream of Caspase-3 activation
Thermo Scientific™ Reagents for EpiJET™ Bisulfite Conversion Kit
Perform on-column desulfonation of converted DNA that has been bound to the membrane of a micro column. Thermo Scientific™ Desulfonation Buffer for EpiJET™ Bisulfite Conversion Kit provides additional reagent for use in bisulfite conversion of DNA for methylation analysis.
Thermo Scientific™ Modification Solution II
Deanimate unmethylated cytosines and convert them to uracils. Thermo Scientific™ EpiJET™ Modification Solution II is a component of the EpiJET™ Bisulfate Conversion Kit (K1461) and may be purchased separately when additional supply is needed for more reactions. Supplied in 0.35mL aliquots.
MilliporeSigma™ Calbiochem™ Marimastat
Used in studying involvement of MMPs in various cellular and pathological processes both in vitro and in vivo
Tocris Bioscience™ 2,3-DCPE hydrochloride
Selectively induces cancer cell apoptosis